Thionyl Chloride → 2-Formyl-5-(trifluoromethyl)benzoyl chloride

HRID 78548Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 78548
[CH:1]([C:3]1[CH:11]=[CH:10][C:9]([C:12]([F:15])([F:14])[F:13])=[CH:8][C:4]=1[C:5](O)=[O:6])=[O:2].S(Cl)([Cl:18])=O>>[CH:1]([C:3]1[CH:11]=[CH:10][C:9]([C:12]([F:15])([F:14])[F:13])=[CH:8][C:4]=1[C:5]([Cl:18])=[O:6])=[O:2]

Komponenten

3

Edukt 2

HCID 24386Thionyl ChlorideHCID 866408592-Formyl-5-(trifluoromethyl)benzoic acid

Produkt 1

HCID 871140332-Formyl-5-(trifluoromethyl)benzoyl chloride

Versuchsvorschrift

A solution of Example 375A (0.6 g) and thionyl chloride (3.27 g, 27.5 mmol) was refluxed for 2 hr. The reaction solution was cooled to room temperature, concentrated, azeotroped with toluene, and used without further purification.

Aufarbeitung

  1. concentrationconcentrated
  2. customazeotroped with toluene
  3. customused without further purification

Quellen und Nachweise

ORD-Eintrag
ord-3ccb49dfcfe84c628b4d5ddde61629b1
Quelldatensatz
uspto-grants-2014_09
Patentnummer
US08841334B2

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