Sodium Sulfite → Ethyl-2-(2-ethoxytetrahydrofuran-3-yl)-2-oxoacetate
Reaktionsgleichung
[CH2:1]([O:3][C:4](=[O:16])[C:5]([C:7]1(Br)[CH2:11][CH2:10][O:9][CH:8]1[O:12][CH2:13][CH3:14])=[O:6])[CH3:2].S([O-])([O-])=O.[Na+].[Na+]>ClCCl>[CH2:1]([O:3][C:4](=[O:16])[C:5]([CH:7]1[CH2:11][CH2:10][O:9][CH:8]1[O:12][CH2:13][CH3:14])=[O:6])[CH3:2]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
Ethyl-2-(3-bromo-2-ethoxytetrahydrofuran-3-yl)-2-oxoacetate (100 g) dissolved in dichloromethane (500 ml). Sodium sulphite solution (15%, 1000 ml) was added to it. Reaction mass was stirred for 8 hrs. Organic and aqueous layer separated dichloromethane layer was washed with water (2×200 ml). Dichloromethane layer was then concentrated to residue to get Ethyl-2-(2-ethoxytetrahydrofuran-3-yl)-2-oxoacetate (Yield 67 g)