HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(3-Aminopropyl)-2-pyrrolidinone → 3-[(2-fluoro-4-iodophenyl)amino]-N-[3-(2-oxopyrrolidin-1-yl)propyl]isonicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(3-Aminopropyl)-2-pyrrolidinone | HCID 82111 | — |
| Edukt | 3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acid | HCID 59026791 | — |
| Produkt | 3-[(2-fluoro-4-iodophenyl)amino]-N-[3-(2-oxopyrrolidin-1-yl)propyl]isonicotinamide | HCID 11648689 | — |
Reaktionsschritte
3-[(2-fluoro-4-iodophenyl)amino]-N-[3-(2-oxopyrrolidin-1-yl)propyl]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.6 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.85 mmol of 1-(3-amino-propyl)-pyrrolidin-2-one LC/MS [8.70 min; 483 (M+1)].
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08841459B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-806cb2c300634d04bb6f023661f7b0f1 |
| Quellennotiz | uspto-grants-2014_09 |