Toluene → [3-(2,2-Difluoro-2-phenyl-ethylamino)-6-methyl-2-oxo-2H-pyrazin-1-yl]-acetic acid ethyl ester

Reaktionsgleichung

[Br:1][c:2]1[c:3](=[O:15])[n:4]([CH2:9][C:10](=[O:11])[O:12][CH2:13][CH3:14])[c:5]([CH3:8])[cH:6][n:7]1.[CH3:27][CH2:28][O:29][C:30](=[O:31])[CH3:32].[CH3:33][c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1.[F:16][C:17]([CH2:18][NH2:19])([c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[F:26]>>[c:2]1([NH:19][CH2:18][C:17]([F:16])([c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[F:26])[c:3](=[O:15])[n:4]([CH2:9][C:10](=[O:11])[O:12][CH2:13][CH3:14])[c:5]([CH3:8])[cH:6][n:7]1