Tetrahydrofuran → Tert-butyl 4-[(6-chloropyrazin-2-yl)(propyl)amino]piperidine-1-carboxylate

Reaktionsgleichung

[Cl:1][c:2]1[cH:3][n:4][cH:5][c:6]([NH:8][CH:9]2[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2)[n:7]1.[I:22][CH2:23][CH2:24][CH3:25].[Na:26].[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1>>[Cl:1][c:2]1[cH:3][n:4][cH:5][c:6]([N:8]([CH:9]2[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2)[CH2:23][CH2:24][CH3:25])[n:7]1