6-(2,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-one → 4-carboxy-2-(4-chlorobenzyl)-6-(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	6-(2,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-one	HCID 21991416	—
Edukt	2-(4-chlorobenzyl)-6-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one	HCID 21991511	—
Produkt	4-carboxy-2-(4-chlorobenzyl)-6-(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one	HCID 21991579	96%

Reaktionsschritte

Following the procedure of Example 1 (7), 2-(4-chlorobenzyl)-6-(3-fluoro-4-methoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one was reacted to yield the title compound as a pale yellow crystalline powder (yield: 96.0%).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07087606B2
Quelldatensatz	uspto-grants-2006_08
ORD ID	ord-d6d1219af12d4e5e8426d879ab02395b
Quellennotiz	uspto-grants-2006_08