4-Amino-5-chloro-thiophene-2-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide → 5-[3-(2,2,2-Trifluoro-ethoxy)-4-trifluoromethyl-phenyl]-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid [2-chloro-5-(2-hydroxy-1,1-dimethyl-ethylsulfamoyl)-thiophen-3-yl]-amide

HRID 802456Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 802456
[F:1][C:2]([CH2:3][O:4][c:5]1[cH:6][c:7](-[c:15]2[n:16][c:17]3[n:18]([c:19]([C:21]([F:22])([F:23])[F:24])[cH:20]2)[n:25][cH:26][c:27]3[C:28](=[O:29])[OH:30])[cH:8][cH:9][c:10]1[C:11]([F:12])([F:13])[F:14])([F:31])[F:32].[OH:33][CH2:34][C:35]([CH3:36])([CH3:37])[NH:38][S:39](=[O:40])(=[O:41])[c:42]1[s:43][c:44]([Cl:48])[c:45]([NH2:47])[cH:46]1>>[F:1][C:2]([CH2:3][O:4][c:5]1[cH:6][c:7](-[c:15]2[n:16][c:17]3[n:18]([c:19]([C:21]([F:22])([F:23])[F:24])[cH:20]2)[n:25][cH:26][c:27]3[C:28](=[O:29])[NH:47][c:45]2[c:44]([Cl:48])[s:43][c:42]([S:39]([NH:38][C:35]([CH2:34][OH:33])([CH3:36])[CH3:37])(=[O:40])=[O:41])[cH:46]2)[cH:8][cH:9][c:10]1[C:11]([F:12])([F:13])[F:14])([F:31])[F:32]

Komponenten

3

Edukt 2

HCID 672187574-Amino-5-chloro-thiophene-2-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amideHCID 866071155-[3-(2,2,2-Trifluoro-ethoxy)-4-trifluoromethyl-phenyl]-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid

Produkt 1

HCID 119973265-[3-(2,2,2-Trifluoro-ethoxy)-4-trifluoromethyl-phenyl]-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid [2-chloro-5-(2-hydroxy-1,1-dimethyl-ethylsulfamoyl)-thiophen-3-yl]-amide

Quellen und Nachweise

ORD-Eintrag
ord-256218a2ac57463bae9d92480136e6da
Quelldatensatz
Test data from https://doi.org/10.1039/C8SC04228D

Notizen zur Reaktion

Wird geladen…