Benzophenone → [Diphenyl(4-methylphenyl)]methanol

Reaktionsgleichung

[C:1]1([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[CH2:17][OH:18])[C:10]2[C:5](=CC=CC=2)[CH:4]=[CH:3][CH:2]=1.[Mg].Br[C:21]1[CH:26]=[CH:25][C:24]([CH3:27])=[CH:23][CH:22]=1.C(C1C=CC=CC=1)(=O)C1C=CC=CC=1>>[C:24]1([C:27]2[C:11]([C:1]3[CH:10]=[CH:5][CH:4]=[CH:3][CH:2]=3)=[C:12]([CH2:17][OH:18])[CH:13]=[CH:14][C:15]=2[CH3:16])[CH:25]=[CH:26][CH:21]=[CH:22][CH:23]=1

Komponenten

Edukt 4

HCID 3102Benzophenone

HCID 78054-Bromotoluene

HCID 5462224Magnesium

HCID 57154374[(Naphthyl)phenyl]methanol

Produkt 1

HCID 67426675[Diphenyl(4-methylphenyl)]methanol

Versuchsvorschrift

With the same method as for Compound 13, a Grignard reagent was prepared from magnesium (Wako Pure Chemical Industries, Ltd.) and p-bromotoluene (Wako Pure Chemical Industries, Ltd.), and benzophenone (Wako Pure Chemical Industries, Ltd.) was allowed to react with the reagent, to thereby obtain the title compound. m.p. 68-71° C.

Aufarbeitung

customto react with the reagent

Quellen und Nachweise

ORD-Eintrag: ord-a4ea7b3575bb42a39ffe1cfca97286af
Quelldatensatz: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08846012B2

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