HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3,4-Dimethoxyphenylboronic acid → 4-[5-(3,4-Dimethoxyphenyl)pyridin-3-yl]-1,4-diazatricyclo[4.3.1.13,8]undecane
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3,4-Dimethoxyphenylboronic acid | HCID 2734702 | — |
| Edukt | 4-(5-Bromopyridin-3-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane | HCID 86649249 | — |
| Produkt | 4-[5-(3,4-Dimethoxyphenyl)pyridin-3-yl]-1,4-diazatricyclo[4.3.1.13,8]undecane | HCID 49869712 | — |
Reaktionsschritte
The title compound was prepared from the product of Example 65A and 3,4-dimethoxyphenylboronic acid according to General Method B: 1H NMR (500 MHz, CDCl3) δ ppm 8.14 (d, 2 H), 7.19 (d, 1 H), 7.07 (d, 2 H), 6.93 (d, 1 H), 4.13 (s, 1 H), 3.91 (s, 3 H), 3.87 (s, 3 H), 3.81-3.30 (m, 7 H), 3.09-2.95 (m, 4 H), 2.34-2.18 (m, 3 H); LC-MS Method D (ESI+) m/z 366.0 (M+H)+, retention time 1.28 minutes.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08846661B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-34352c502dcd48a9a5f9f9aad989801d |
| Quellennotiz | uspto-grants-2014_09 |