HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Pyridine → ethyl 3,5-dimethyl-1-(4-methylphenyl)-1H-pyrazole-4-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Pyridine | HCID 1049 | — |
| Edukt | (4-Methylphenyl)hydrazine | HCID 10875 | — |
| Edukt | Ethyl 2-acetylacetoacetate | HCID 79063 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | ethyl 3,5-dimethyl-1-(4-methylphenyl)-1H-pyrazole-4-carboxylate | HCID 2766289 | — |
Reaktionsschritte
Similar to Example 1, p-tolylhydrazine (10 mmol, 1.8 g) and 2-acetyl-3-oxo-butyric acid ethyl ester (10 mmol, 1.7 g) were mixed in a solution of 50% pyridine in ethanol. The solvents were removed under vacuum. The named product was purified over silica gel (m.p. 47° C.–49° C.).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07087634B2 |
| Quelldatensatz | uspto-grants-2006_08 |
| ORD ID | ord-8a2a370daa1e478a88c3bf3e9f78a9ca |
| Quellennotiz | uspto-grants-2006_08 |