4-Cyanobenzoyl chloride → 4-{3-[6-(4-Isopropylpiperazin-1-yl)pyridin-3-yl][1,2,4]oxadiazol-5-yl}benzonitrile, hydrochloride

HRID 80900

Reaktionsgleichung

Reaktionsgleichung von HRID 80900
[OH:1][NH:2][C:3](=[NH:19])[C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][N:13]([CH:16]([CH3:18])[CH3:17])[CH2:12][CH2:11]2)=[N:6][CH:5]=1.[C:20]([C:22]1[CH:30]=[CH:29][C:25]([C:26]([Cl:28])=O)=[CH:24][CH:23]=1)#[N:21]>>[ClH:28].[CH:16]([N:13]1[CH2:12][CH2:11][N:10]([C:7]2[N:6]=[CH:5][C:4]([C:3]3[N:19]=[C:26]([C:25]4[CH:29]=[CH:30][C:22]([C:20]#[N:21])=[CH:23][CH:24]=4)[O:1][N:2]=3)=[CH:9][CH:8]=2)[CH2:15][CH2:14]1)([CH3:17])[CH3:18]

Komponenten

3

Versuchsvorschrift

The title compound was prepared by a similar procedure to that described in Example 41, starting from N-hydroxy-6-(4-isopropylpiperazin-1-yl)nicotinamidine and 4-cyanobenzoylchloride.

Quellen und Nachweise

ORD-Eintrag
ord-919ee0a763ea4beabcd899f0b3ffc624
Quelldatensatz
uspto-grants-2014_09
Patentnummer
US08846677B2

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