HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl vinyl sulfone → {2-[7-(2-Methanesulfonyl-vinyl)-1H-indol-3-yl)-1,1-dimethyl-ethyl}-carbamic acid tert-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl vinyl sulfone | HCID 19354 | — |
| Edukt | [1,1-dimethyl-2-(7-trifluoromethanesulfonyhnethyl-1H-indol-3-yl)-ethyl]-carbamic acid tert-butyl ester | HCID 69517369 | — |
| Produkt | {2-[7-(2-Methanesulfonyl-vinyl)-1H-indol-3-yl)-1,1-dimethyl-ethyl}-carbamic acid tert-butyl ester | HCID 86595247 | — |
Reaktionsschritte
{2-[7-(2-Methanesulfonyl-vinyl)-1H-indol-3-yl)-1,1-dimethyl-ethyl}-carbamic acid tert-butyl ester is prepared from [1,1-dimethyl-2-(7-trifluoromethanesulfonylmethyl-1H-indol-3-yl)-ethyl]-carbamic acid tert-butyl ester and methyl vinyl sulfone as described for the preparation of Amine 23 (98%). FDMS m/e=392.2 (M++1).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07087635B2 |
| Quelldatensatz | uspto-grants-2006_08 |
| ORD ID | ord-6bb9173e2bfb4e009592dee1e206c9e3 |
| Quellennotiz | uspto-grants-2006_08 |