HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Nitroethane → 6-fluoro-5-methoxy-3-(2-nitro-propenyl)-1H-indole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Nitroethane | HCID 6587 | — |
| Edukt | Ammonium Acetate | HCID 517165 | — |
| Edukt | 6-fluoro-5-methoxy-1H-indole-3-carbaldehyde | HCID 22014804 | — |
| Produkt | 6-fluoro-5-methoxy-3-(2-nitro-propenyl)-1H-indole | HCID 69516792 | 92% |
Reaktionsbedingungen
| Temperatur | 100 °C |
|---|
Reaktionsschritte
A mixture of nitroethane(44 ml, 611 mmol), 6-fluoro-5-methoxy-1H-indole-3-carbaldehyde (11.8 g, 61 mmol), and ammonium acetate(1.78 g, 23 mmol) is stirred at 100° C. for 3 hours, allowed to cool, and is filtered to give 14 g of 6-fluoro-5-methoxy-3-(2-nitro-propenyl)-1H-indole (92%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07087635B2 |
| Quelldatensatz | uspto-grants-2006_08 |
| ORD ID | ord-a2dc7544472245ceae1897b7f180e6d7 |
| Quellennotiz | uspto-grants-2006_08 |