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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 81502Erstellt: 25. Oktober 2026

Water → tert-Butyl [2,6-dimethyl-4-(5-methylsulfanyl-7-propoxyoxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]acetate

https://huagongshe.com/reaction/81502

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktWaterHCID 962—
EduktPotassium CarbonateHCID 11430—
Edukttert-Butyl bromoacetateHCID 79177—
Edukt2,6-Dimethyl-4-(5-methylsulfanyl-7-propoxyoxazolo[5,4-d]pyrimidin-2-yl)phenolHCID 136389866—
LösungsmittelDimethylformamideHCID 6228—
Produkttert-Butyl [2,6-dimethyl-4-(5-methylsulfanyl-7-propoxyoxazolo[5,4-d]pyrimidin-2-yl)-phenoxy]acetateHCID 86688232—

Reaktionsschritte

3.20 g of potassium carbonate and then 0.93 ml of tert-butyl bromoacetate were added to a solution of 2.00 g of 2,6-dimethyl-4-(5-methylsulfanyl-7-propoxyoxazolo[5,4-d]pyrimidin-2-yl)phenol in 20 ml of N,N-dimethylformamide. The mixture was reacted at 60° C. for 1 h and then allowed to cool and poured into water. The precipitate obtained was filtered off with suction and dried under reduced pressure. This gave 2.45 g of the title compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08846691B2
Quelldatensatzuspto-grants-2014_09
ORD IDord-1fe2590e9b5b43a697d634712d8aefba
Quellennotizuspto-grants-2014_09