HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dimethylamine tetrahydrofuran → 6-({5-[2-(dimethylamino)ethoxy]pyridin-2-yl}oxy)-N-pyrazin-2-ylquinazoline-4-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dimethylamine tetrahydrofuran | HCID 22320367 | — |
| Edukt | 5-(2,2-Diethoxyethoxy)-2-fluoropyridine | HCID 68429706 | — |
| Edukt | 4-(Pyrazin-2-ylamino)quinazolin-6-ol | HCID 136334744 | — |
| Produkt | 6-({5-[2-(dimethylamino)ethoxy]pyridin-2-yl}oxy)-N-pyrazin-2-ylquinazoline-4-amine | HCID 59508840 | — |
Reaktionsschritte
Using 4-(pyrazin-2-ylamino)quinazolin-6-ol, 5-(2,2-diethoxyethoxy)-2-fluoropyridine and 2 M dimethylamine/tetrahydrofuran solution, and in the same manner as in Example 31 or according to a method similar to it or according to a combination thereof with an ordinary method, the entitled compound (13 mg) was obtained as a pale yellow amorphous solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08846700B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-3488a865315b4999b43bea5c38d6c3c2 |
| Quellennotiz | uspto-grants-2014_09 |