2-Indancarboxylic Acid → N-{5-[(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)carbonyl]pyridin-3-yl}indane-2-carboxamide

HRID 82116Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 82116
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]([C:10]2[C:18]3[CH:17]=[N:16][CH:15]=[N:14][C:13]=3[N:12]([CH3:19])[CH:11]=2)=[O:9])[CH:5]=[N:6][CH:7]=1.[CH2:20]1[C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH2:22][CH:21]1[C:29](O)=[O:30]>>[CH3:19][N:12]1[C:13]2[N:14]=[CH:15][N:16]=[CH:17][C:18]=2[C:10]([C:8]([C:4]2[CH:3]=[C:2]([NH:1][C:29]([CH:21]3[CH2:22][C:23]4[C:28](=[CH:27][CH:26]=[CH:25][CH:24]=4)[CH2:20]3)=[O:30])[CH:7]=[N:6][CH:5]=2)=[O:9])=[CH:11]1

Komponenten

3

Edukt 2

HCID 5757772-Indancarboxylic AcidHCID 70817432(5-aminopyridin-3-yl)(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone

Produkt 1

HCID 70817814N-{5-[(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)carbonyl]pyridin-3-yl}indane-2-carboxamide

Versuchsvorschrift

The title compound was prepared according to the method described for Library protocol 1 starting from (5-amino-pyridin-3-yl)-(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methanone (Preparation 110) and indane-2-carboxylic acid to afford the title compound. LCMS: Rt=2.58 min; m/z 398 [M+H].

Aufarbeitung

  1. customThe title compound was prepared

Quellen und Nachweise

ORD-Eintrag
ord-2ebbcab1c7d245c08e78412596dfa5f8
Quelldatensatz
uspto-grants-2014_09
Patentnummer
US08846698B2

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