HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Cyanophenylacetic acid → N-(5-{[7-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl}pyridin-3-yl)-2-(4-cyanophenyl)acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Cyanophenylacetic acid | HCID 79587 | — |
| Edukt | Diisopropylethylamine | HCID 81531 | — |
| Edukt | (5-aminopyridin-3-yl)[7-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]methanone | HCID 70817221 | — |
| Produkt | N-(5-{[7-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl}pyridin-3-yl)-2-(4-cyanophenyl)acetamide | HCID 70817571 | — |
Reaktionsschritte
Prepared according to the method described for Example 1 using (5-aminopyridin-3-yl)[7-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]methanone (Preparation 38), and 4-cyanophenylacetic acid with DIPEA.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08846698B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-e0aa00fb286b4d8a85cf988895ac714b |
| Quellennotiz | uspto-grants-2014_09 |