Sodium Hydroxide → 6-Amino-4-(2-furyl)-1H-pyrazolo[3,4-d]pyrimidin-1-ylacetic acid

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Sodium Hydroxide	HCID 14798	—
Edukt	ethyl 6-amino-4-(2-furyl)-1H-pyrazolo[3,4-d]pyrimidin-1-ylacetate	HCID 22015527	—
Lösungsmittel	Methanol	HCID 887	—
Produkt	6-Amino-4-(2-furyl)-1H-pyrazolo[3,4-d]pyrimidin-1-ylacetic acid	HCID 22015531	95%

Reaktionsschritte

A solution of ethyl 6-amino-4-(2-furyl)-1H-pyrazolo[3,4-d]pyrimidin-1-ylacetate (350 mg, 1.22 mmol) in MeOH (2 mL) was treated with NaOH (1-M, 1 mL, 1 mmol), refluxed for 15 min, cooled, acidified and filtered to give the title compound (300 mg, 95%) as a white solid.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07087754B2
Quelldatensatz	uspto-grants-2006_08
ORD ID	ord-5e488aaa93084100a887369eb5c0f859
Quellennotiz	uspto-grants-2006_08