Tetrahydrofuran → 4-[2-[(5-fluoro-6-methoxy-3-pyridinyl)amino]-5-[(2-methyl-4-methylsulfonylpiperazin-1-yl)methyl]-3-pyridinyl]-N,N-bis[(4-methoxyphenyl)methyl]-6-methyl-1,3,5-triazin-2-amine

HRID 831164Notizen

Reaktionsgleichung

[CH2:66]1[O:67][CH2:68][CH2:69][CH2:70]1.[CH3:57][Si:58]([N-:59][Si:60]([CH3:61])([CH3:62])[CH3:63])([CH3:64])[CH3:65].[F:11][c:12]1[n:13][cH:14][c:15]([CH2:44][N:45]2[CH:46]([CH3:55])[CH2:47][N:48]([S:51](=[O:52])(=[O:53])[CH3:54])[CH2:49][CH2:50]2)[cH:16][c:17]1-[c:18]1[n:19][c:20]([N:25]([CH2:26][c:27]2[cH:28][cH:29][c:30]([O:33][CH3:34])[cH:31][cH:32]2)[CH2:35][c:36]2[cH:37][cH:38][c:39]([O:42][CH3:43])[cH:40][cH:41]2)[n:21][c:22]([CH3:24])[n:23]1.[F:1][c:2]1[cH:3][c:4]([NH2:10])[cH:5][n:6][c:7]1[O:8][CH3:9].[Li+:56]>>[F:1][c:2]1[cH:3][c:4]([NH:10][c:12]2[n:13][cH:14][c:15]([CH2:44][N:45]3[CH:46]([CH3:55])[CH2:47][N:48]([S:51](=[O:52])(=[O:53])[CH3:54])[CH2:49][CH2:50]3)[cH:16][c:17]2-[c:18]2[n:19][c:20]([N:25]([CH2:26][c:27]3[cH:28][cH:29][c:30]([O:33][CH3:34])[cH:31][cH:32]3)[CH2:35][c:36]3[cH:37][cH:38][c:39]([O:42][CH3:43])[cH:40][cH:41]3)[n:21][c:22]([CH3:24])[n:23]2)[cH:5][n:6][c:7]1[O:8][CH3:9]