(1,1'-Biphenyl)-4-sulphonyl chloride → 1-([1,1'-Biphenyl]-4-yl-sulfonyl)-4-(1-piperazinyl)-1H-indole Hydrochloride

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	(1,1'-Biphenyl)-4-sulphonyl chloride	HCID 74192	—
Edukt	tert-Butyl 4-(1H-indol-4-yl)piperazine-1-carboxylate	HCID 22015386	—
Produkt	1-([1,1'-Biphenyl]-4-yl-sulfonyl)-4-(1-piperazinyl)-1H-indole Hydrochloride	HCID 10226082	—

Reaktionsschritte

The title compound was prepared from 4-(4-boc-piperazinyl)-indole and 1,1 ′-biphenyl-4-ylsulfonyl chloride according to Method 3: 1H NMR (270 MHz, DMSO-d6) δ 9.26 (br, 1H), 8.04 (m, 2 H), 7.88 (m, 3 H), 7.67 (m, 3 H), 7.46 (m, 3 H), 7.27 (t, J=8 Hz, 1 H), 6.96 (d, J=5 Hz, 1 H), 6.80 (d, J=8 Hz, 1 H), 3.25 (m, 8 H); MS (ESI+) for m/z 418 (M+H)+.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07087750B2
Quelldatensatz	uspto-grants-2006_08
ORD ID	ord-1abf8353d6f14c0799bcdf82ec791499
Quellennotiz	uspto-grants-2006_08