HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Pyridine-3-sulfonyl chloride → 4-(1-Piperazinyl)-1-(3-pyridinylsulfonyl)-1H-indole Hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Pyridine-3-sulfonyl chloride | HCID 3164136 | — |
| Edukt | tert-Butyl 4-(1H-indol-4-yl)piperazine-1-carboxylate | HCID 22015386 | — |
| Produkt | 4-(1-Piperazinyl)-1-(3-pyridinylsulfonyl)-1H-indole Hydrochloride | HCID 22015331 | — |
Reaktionsschritte
The title compound was prepared from 4-(4-boc-piperazinyl)-indole and 3-pyridinylsulfonyl chloride according to Method 3: 1H NMR (270 MHz, DMSO-d6) δ 9.37 (br, 1 H), 9.18 (d, J=3 Hz, 1 H), 8.86 (d, J=5 Hz, 1 H), 8.39 (d, J=8 Hz, 1 H), 7.85 (d, J=3 Hz, 1 H), 7.70–7.60 (m, 2 H), 7.27 (t, J=8 Hz, 1 H), 7.00 (d, J=3 Hz, 1 H), 6.82 (d, J=8 Hz, 1 H), 3.24 (m, 8 H); MS (ESI+) for m/z 343 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07087750B2 |
| Quelldatensatz | uspto-grants-2006_08 |
| ORD ID | ord-81dc0901bd474a4e965d348614b33633 |
| Quellennotiz | uspto-grants-2006_08 |