2-Amino-4-methyl-thiazole-5-sulfonic acid (2-hydroxy-1-hydroxymethyl-1-methyl-ethyl)-amide → 5-(3-Ethoxy-4-trifluoromethyl-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid [5-(2-hydroxy-1-hydroxymethyl-1-methyl-ethylsulfamoyl)-4-methyl-thiazol-2-yl]-amide

Reaktionsgleichung

[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6](-[c:14]2[n:15][c:16]3[n:17]([c:18]([C:20]([F:21])([F:22])[F:23])[cH:19]2)[n:24][cH:25][c:26]3[C:27](=[O:28])[OH:29])[cH:7][cH:8][c:9]1[C:10]([F:11])([F:12])[F:13].[OH:30][CH2:31][C:32]([CH3:33])([CH2:34][OH:35])[NH:36][S:37](=[O:38])(=[O:39])[c:40]1[c:41]([CH3:46])[n:42][c:43]([NH2:45])[s:44]1>>[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6](-[c:14]2[n:15][c:16]3[n:17]([c:18]([C:20]([F:21])([F:22])[F:23])[cH:19]2)[n:24][cH:25][c:26]3[C:27](=[O:28])[NH:45][c:43]2[n:42][c:41]([CH3:46])[c:40]([S:37]([NH:36][C:32]([CH2:31][OH:30])([CH3:33])[CH2:34][OH:35])(=[O:38])=[O:39])[s:44]2)[cH:7][cH:8][c:9]1[C:10]([F:11])([F:12])[F:13]