HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethylamine → HCID 68444860, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethylamine | HCID 6341 | — |
| Edukt | 6-(3-Pyridin-2-yl-isoxazol-4-ylmethoxy)-nicotinic acid | HCID 68445257 | — |
| Produkt | HCID 68444860 | HCID 68444860 | 81% |
Reaktionsschritte
As described for example 358 g, 6-(3-pyridin-2-yl-isoxazol-4-ylmethoxy)-nicotinic acid (100 mg, 0.34 mmol) was converted using ethylamine (2 M solution in THF) instead of 4-aminotetrahydropyran to the title compound (88 mg, 81%) which was obtained as a white solid. MS: m/e=325.3 [M−H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08846719B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-3ba25d6c071a4d20a12124b203f9d447 |
| Quellennotiz | uspto-grants-2014_09 |