1-((Tert-butoxy)carbonyl)pyrrolidine-3-carboxylic acid → tert-butyl 3-[[3-[(5-methyl-6-oxo-8-propan-2-yl-7H-pteridin-2-yl)amino]-5-methylsulfonylphenyl]carbamoyl]pyrrolidine-1-carboxylate

Reaktionsgleichung

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:13](=[O:14])[OH:15])[CH2:11][CH2:12]1.[NH2:16][c:17]1[cH:18][c:19]([NH:27][c:28]2[n:29][c:30]3[c:35]([cH:36][n:37]2)[N:34]([CH3:38])[C:33](=[O:39])[CH2:32][N:31]3[CH:40]([CH3:41])[CH3:42])[cH:20][c:21]([S:23](=[O:24])(=[O:25])[CH3:26])[cH:22]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:13](=[O:15])[NH:16][c:17]2[cH:18][c:19]([NH:27][c:28]3[n:29][c:30]4[c:35]([cH:36][n:37]3)[N:34]([CH3:38])[C:33](=[O:39])[CH2:32][N:31]4[CH:40]([CH3:41])[CH3:42])[cH:20][c:21]([S:23](=[O:24])(=[O:25])[CH3:26])[cH:22]2)[CH2:11][CH2:12]1