Methyl iodide → 7-Methyl-8-oxo-2H,8H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinolin-7-ium iodide

HRID 838929Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 838929
[CH:1]1[CH:2]=[CH:3][C:4]2[C:14](=[O:15])[C:13]3[C:8]4[C:9](=[CH:16][C:17]5[O:21][CH2:20][O:19][C:18]=5[C:7]=4[C:5]=2[CH:6]=1)[CH:10]=[CH:11][N:12]=3.[I:22][CH3:23]>C(Cl)(Cl)Cl>[CH3:23][N+:12]1[CH:11]=[CH:10][C:9]2[C:8]3=[C:7]([C:18]4[O:19][CH2:20][O:21][C:17]=4[CH:16]=2)[C:5]2[C:4]([C:14](=[O:15])[C:13]=13)=[CH:3][CH:2]=[CH:1][CH:6]=2.[I-:22]

Komponenten

4

Edukt 2

HCID 6328Methyl iodideHCID 10144Liriodenine2×

Produkt 1

HCID 1227727-Methyl-8-oxo-2H,8H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinolin-7-ium iodide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6212ChloroformLösungsmittel

Versuchsvorschrift

Liriodenine methiodide was prepared from the liriodenine isolated in accordance with Example 1. A 2.71 gm sample of liriodenine was reflexed in 30 ml of chloroform and then 10 ml of iodomethane was added. After 24 hours at reflux, the solution was cooled, excess iodomethane removed, and the red crystals filtered. Crystallization from methanol yielded 2.24 gm liriodenine methiodide, mp 235 d.

Aufarbeitung

  1. customisolated in accordance with Example 1
  2. temperatureAfter 24 hours at reflux
  3. temperaturethe solution was cooled
  4. customexcess iodomethane removed
  5. filtrationthe red crystals filtered
  6. customCrystallization from methanol

Quellen und Nachweise

ORD-Eintrag
ord-b406a0fd906441c69e7be19269da442f
Quelldatensatz
uspto-grants-1978_06
Patentnummer
US04093717

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