Methanol → Methyl 3-nitro-4-phenoxy-5-sulfamoylbenzoate

HRID 839051Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 839051
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([S:20](=[O:23])(=[O:22])[NH2:21])[C:12]=1[O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:7]([OH:9])=[O:8])([O-:3])=[O:2].OS(O)(=O)=O.[CH3:29]O>>[CH3:29][O:8][C:7](=[O:9])[C:6]1[CH:10]=[C:11]([S:20](=[O:23])(=[O:22])[NH2:21])[C:12]([O:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=1

Komponenten

4

Edukt 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 1199263-(Aminosulfonyl)-5-nitro-4-phenoxybenzoic acid

Produkt 1

HCID 53854447Methyl 3-nitro-4-phenoxy-5-sulfamoylbenzoate

Versuchsvorschrift

34 g (~0.1 mol) of 3-nitro-4-phenoxy-5-sulphamylbenzoic acid are dissolved in 150 ml of methanol and are heated to the boil. 5.4 ml of concentrated H2SO4 are then added slowly dropwise and the mixture is heated at reflux temperature for 10 hours. On cooling, 3-nitro-4-phenoxy-5-sulphamylbenzoic acid methyl ester crystallises.

Aufarbeitung

  1. temperatureare heated to the boil
  2. temperaturethe mixture is heated
  3. temperatureat reflux temperature for 10 hours
  4. temperatureOn cooling
  5. custom3-nitro-4-phenoxy-5-sulphamylbenzoic acid methyl ester crystallises

Quellen und Nachweise

ORD-Eintrag
ord-9c90410b58b24496a7ca32f91933ce0b
Quelldatensatz
uspto-grants-1978_06
Patentnummer
US04093735

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