8-Acetyl-11-(1-hydroxycyclohexyl)undec-10-ynoic acid → 8-Acetyl-11-(1-hydroxycyclohexyl)undecanoic acid
Reaktionsgleichung
[C:1]([CH:4]([CH2:14][C:15]#[C:16][C:17]1([OH:23])[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1)[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]([OH:13])=[O:12])(=[O:3])[CH3:2].C(C(CC#C[C@@H](O)CCCCC)CCCCCCC(O)=O)(=O)C>>[C:1]([CH:4]([CH2:14][CH2:15][CH2:16][C:17]1([OH:23])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]1)[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]([OH:13])=[O:12])(=[O:3])[CH3:2]Komponenten
3
Versuchsvorschrift
This compound is prepared essentially by the same hydrogenation procedure described in Example 36, Step C, except that 8 -acetyl-11-(1-hydroxycyclohexyl)-10-undecynoic acid (Example 39) is substituted for 8-acetyl-12-(S)-hydroxy-10-heptadecynoic acid. The product is obtained as a yellowish viscous oil; pmr (CDCl3) δ 2.08 (3H,s CH3CO), δ6.52 (2H,s OH and COOH). Anal. Calcd. for C19H34O4 : C, 69.90; H, 10.50; Found: C, 70.23; H, 10.70.
Aufarbeitung
- customThis compound is prepared essentially by the same hydrogenation procedure