(Z)-Benzaldehyde oxime → Methyl 3-phenylisoxazole-4-carboxylate
Reaktionsgleichung
F[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:12]([C:13]([O:15][CH3:16])=[O:14])=[CH:11][O:10][N:9]=2)=[CH:4][CH:3]=1.C(=NO)C1C=CC=CC=1>>[C:5]1([C:8]2[C:12]([C:13]([O:15][CH3:16])=[O:14])=[CH:11][O:10][N:9]=2)[CH:4]=[CH:3][CH:2]=[CH:7][CH:6]=1Komponenten
3
Versuchsvorschrift
This compound was synthesised following the procedure described for Compound 8C but using benzaldoxime instead of 4-fluorobenzaldoxime as a starting material. The crude was purified twice by flash chromatography (toluene-acetone 96:4 followed by toluene) to give the title compound as an oil (35%).
Aufarbeitung
- customThis compound was synthesised
- customThe crude was purified twice by flash chromatography (toluene-acetone 96:4 followed by toluene)
Quellen und Nachweise
- ORD-Eintrag
- ord-cfdb9f3188974a09821b1fe5d45b71e2
- Quelldatensatz
- uspto-grants-2002_04
- Patentnummer
- US06365591B1
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