Hydrogen Bromide → 1-Bromo-3,7-dimethyloctane

Reaktionsgleichung

S(=O)(=O)(O)O.[CH3:6][CH:7]([CH2:11][CH2:12][CH2:13][CH:14]([CH3:16])[CH3:15])[CH2:8][CH2:9]O.[BrH:17]>>[CH3:6][CH:7]([CH2:11][CH2:12][CH2:13][CH:14]([CH3:16])[CH3:15])[CH2:8][CH2:9][Br:17]

Komponenten

Edukt 3

HCID 260Hydrogen Bromide

HCID 1118Sulfuric Acid

HCID 77923,7-Dimethyl-1-octanol

Produkt 1

HCID 1379141-Bromo-3,7-dimethyloctaneAusbeute 82,1 %

Versuchsvorschrift

48% HBr (200 ml) and concentrated sulfuric acid (0.46 ml) were added to 3,7-dimethyl-1-octanol (21.0 g, 157.9 mmol), and the mixture was heated overnight. After allowing to cool to room temperature, and the mixture was extracted with hexane. The organic layer was washed with 5% aqueous sodium hydrogen carbonate solution and saturated brine, dried and concentrated to give the title compound (28.7 g, 82.1%).

Aufarbeitung

temperaturethe mixture was heated overnight
extractionthe mixture was extracted with hexane
washThe organic layer was washed with 5% aqueous sodium hydrogen carbonate solution and saturated brine
customdried
concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag: ord-68ffd444f96c4333a3dda341ab53f8fc
Quelldatensatz: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08846885B2

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