3-Chlorobenzylideneacetone → 4-(3-Chlorophenyl)butan-2-one
Reaktionsgleichung
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10](=[O:12])[CH3:11])[CH:5]=[CH:6][CH:7]=1.[H][H]>C(O)C.[Pt]=O>[Cl:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][C:10](=[O:12])[CH3:11])[CH:5]=[CH:6][CH:7]=1Komponenten
5
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
1-(3-Chlorophenyl)-1-buten-3-one (20.0 g, 111 mmol) was subjected to hydrogen catalytic reduction in ethanol (200 ml) at room temperature by using platinum oxide (PtO2; 0.30 g) as a catalyst. The catalyst was filtered off and the resulting filtrate was concentrated under reduced pressure. The resulting residue was purified by a silica gel column chromatography to obtain 11.1 g of 1-(3-chlorophenyl)butan-3-one.
Aufarbeitung
- filtrationThe catalyst was filtered off
- concentrationthe resulting filtrate was concentrated under reduced pressure
- customThe resulting residue was purified by a silica gel column chromatography
Quellen und Nachweise
- ORD-Eintrag
- ord-87a6163a9cd54890a32d9ee6d8468af8
- Quelldatensatz
- uspto-grants-2002_04
- Patentnummer
- US06369110B1
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