Hydrochloric Acid → HCID 22617787, Verbindung

HRID 842073Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 842073
[CH2:1]([N:8]([CH2:29][CH3:30])[C:9](=[O:28])[CH2:10][N:11]1[C:19](=[O:20])[N:18]([CH3:21])[C:17]2[C:12]1=[N:13][C:14]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)=[N:15][CH:16]=2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:31]>C(O)C>[ClH:31].[CH2:1]([N:8]([CH2:29][CH3:30])[C:9](=[O:28])[CH2:10][N:11]1[C:19](=[O:20])[N:18]([CH3:21])[C:17]2[C:12]1=[N:13][C:14]([C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1)=[N:15][CH:16]=2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 6433109Emapunil

Produkt 1

HCID 22617787HCID 22617787, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel2×

Versuchsvorschrift

To a mixture of N-benzyl-N-ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-acetamide (0.8 g) obtained in Example 146 and ethanol (15 ml) is added 30% hydrochloric acid in ethanol (15 ml) at 80° C., and the mixture is stirred for 30 minutes. The reaction mixture is cooled to room temperature, and the precipitates are collected by filtration, and washed with ethanol to give the desired compound (0.85 g).

Aufarbeitung

  1. filtrationthe precipitates are collected by filtration
  2. washwashed with ethanol

Quellen und Nachweise

ORD-Eintrag
ord-88a8a3c6fdba4222a3d86421b74442b2
Quelldatensatz
uspto-grants-2002_04
Patentnummer
US06372740B1

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