p-Toluenesulfonic acid → 3-hydroxy-N'-(1-methylethylidene)-2-naphthohydrazide

HRID 844394Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 844394
[OH:1][C:2]1[C:3]([C:12]([NH:14][NH2:15])=[O:13])=[CH:4][C:5]2[C:10]([CH:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.[C:16]1(C)[CH:21]=CC(S(O)(=O)=O)=C[CH:17]=1>CC(C)=O>[OH:1][C:2]1[C:3]([C:12]([NH:14][N:15]=[C:16]([CH3:21])[CH3:17])=[O:13])=[CH:4][C:5]2[C:10]([CH:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2

Komponenten

4

Edukt 2

HCID 6101p-Toluenesulfonic acidHCID 726993-Hydroxy-2-naphthoic acid hydrazide

Produkt 1

HCID 45219753-hydroxy-N'-(1-methylethylidene)-2-naphthohydrazide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Reaktionsbedingungen

Temperatur
20 °C

Versuchsvorschrift

A four neck flask (3 liters) equipped with a thermometer, a reflux condenser and a stirrer was charged with 121.2 g (0.6 mol) of 3-hydroxy-2-naphthohydrazide, 1.14 g (0.006 mol) of p-toluenesulfonic acid and 2 liters of acetone and then heated under reflux for 5 hours. The reaction liquid was cooled down to 20° C. or lower, and then crystal was filtered off and dried under reduced pressure, whereby the intended compound (slightly yellow crystal) was obtained.

Aufarbeitung

  1. customA four neck flask (3 liters) equipped with a thermometer, a reflux condenser and a stirrer
  2. temperatureheated
  3. temperatureunder reflux for 5 hours
  4. customThe reaction liquid
  5. filtrationlower, and then crystal was filtered off
  6. customdried under reduced pressure, whereby the intended compound (slightly yellow crystal)
  7. customwas obtained

Quellen und Nachweise

ORD-Eintrag
ord-5d6f44b48cc54f7980cfe0dbf05aba55
Quelldatensatz
uspto-grants-2002_04
Patentnummer
US06380288B1

Notizen zur Reaktion

Wird geladen…