Acetone → N'-(propan-2-ylidene)isonicotinohydrazide
Reaktionsgleichung
[C:1]([NH:9][NH2:10])(=[O:8])[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.[CH3:11][C:12]([CH3:14])=O>>[CH3:11][C:12](=[N:10][NH:9][C:1](=[O:8])[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1)[CH3:14]Komponenten
3
Reaktionsbedingungen
- Temperatur
- 20 °C
Versuchsvorschrift
A four neck flask (1 liter) equipped with a thermometer, a reflux condenser and a stirrer was charged with 68.5 g (0.5 mol) of isonicotinohydrazide and 500 ml of acetone and then heated under reflux for 24 hours. The reaction liquid was cooled down to 20° C. or lower, and then crystal was filtered off and dried under reduced pressure, whereby the intended compound (white crystal) was obtained.
Aufarbeitung
- customA four neck flask (1 liter) equipped with a thermometer, a reflux condenser and a stirrer
- temperatureheated
- temperatureunder reflux for 24 hours
- customThe reaction liquid
- filtrationlower, and then crystal was filtered off
- customdried under reduced pressure, whereby the intended compound (white crystal)
- customwas obtained
Quellen und Nachweise
- ORD-Eintrag
- ord-c3f313a0529d4c6bbcb1afb3ba6737ff
- Quelldatensatz
- uspto-grants-2002_04
- Patentnummer
- US06380288B1
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