2-Bromo-6-methylbenzoic acid → HCID 69335840, Verbindung

HRID 844850

Reaktionsgleichung

Reaktionsgleichung von HRID 844850
C[O:2][C:3](=[O:24])[C@H:4]([CH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[C:14](=[O:23])[N:15]([CH3:22])[C:16](=[O:21])[N:17]([CH3:20])[C:18]=2[CH3:19])=[CH:9][CH:8]=1)[NH2:5].[Br:25][C:26]1[CH:34]=[CH:33][CH:32]=[C:31]([CH3:35])[C:27]=1[C:28](O)=[O:29]>>[Br:25][C:26]1[CH:34]=[CH:33][CH:32]=[C:31]([CH3:35])[C:27]=1[C:28]([NH:5][C@H:4]([C:3]([OH:2])=[O:24])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[C:14](=[O:23])[N:15]([CH3:22])[C:16](=[O:21])[N:17]([CH3:20])[C:18]=2[CH3:19])=[CH:9][CH:8]=1)=[O:29]

Komponenten

3

Edukt 2

HCID 27355892-Bromo-6-methylbenzoic acidHCID 693369754-(1,3,6-trimethyl-2,4-dioxo-5-pyrimidinyl)-L-phenylalanine methyl ester

Produkt 1

HCID 69335840HCID 69335840, Verbindung

Versuchsvorschrift

N-[(2-bromo-6-methylphenyl)carbonyl]-4-(1,3,6-trimethyl-2,4-dioxo-5-pyrimidinyl)-L-phenylalanine was prepared from 4-(1,3,6-trimethyl-2,4-dioxo-5-pyrimidinyl)-L-phenylalanine methyl ester and 2-bromo-6-methylbenzoic acid using the general procedures described in example 7 and was obtained as a white solid: mp 240-242° C. FAB-HRMS m/e calcd for C24H24BrN3O5 (M+H) 514.0978, found 514.0965.

Aufarbeitung

  1. customwas obtained as a white solid

Quellen und Nachweise

ORD-Eintrag
ord-905cf08e4be54333872800debcccb844
Quelldatensatz
uspto-grants-2002_04
Patentnummer
US06380387B1

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