HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
[3-(Hydroxymethyl)phenyl]boronic acid → N-(2-chlorophenyl)-8-(3-(hydroxymethyl)phenyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | [3-(Hydroxymethyl)phenyl]boronic acid | HCID 2734662 | — |
| Edukt | 8-bromo-N-(2-chlorophenyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide | HCID 44242427 | — |
| Produkt | N-(2-chlorophenyl)-8-(3-(hydroxymethyl)phenyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide | HCID 44241822 | — |
Reaktionsschritte
Following the procedure of Example 93, 8-bromo-N-(2-chlorophenyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide 150 and 3-hydroxymethylphenylboronic acid were reacted to give 201. MS: (ESI+) 476.16
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08846762B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-3fdf7e9c016e422db07da099f429eb8a |
| Quellennotiz | uspto-grants-2014_09 |