Benzenamine, 2-chloro-N-methyl- → n-(2-Chlorophenyl)-n,4,4-trimethyl-4h-thieno[3,2-c]chromene-2-carboxamide

Beteiligte Stoffe

Reaktionsschritte

To a solution of 2-chloro-N-methylaniline (32.10 uL, 0.2750 mmol) in 1.2 M of Pyridine in methylene chloride (0.8333 mL) was added a pinch of DMAP, followed by the addition of 4,4-dimethyl-4H-thieno[3,2-c]chromene-2-carbonyl chloride (70.2 mg, 0.250 mmol). The reaction was stirred at room temperature under N2 with LC/MS monitor. The crude product was purified on silica to give 30 mg 141bp. Yield=31% of theoretical. MS: (ESI+)=385

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