2-Chlorobenzamide → 1-(2-Chlorobenzoyl)-3-(5-trifluoromethyl-2-pyrazinyl)urea

Beteiligte Stoffe

Reaktionsschritte

A compound of formula I may also be prepared by allowing a 2-substituted benzamide to react with a 2-pyrazinylisocyanate utilizing the appropriate solvents, times of reaction and general reaction conditions hereinabove described. For example, 2-chlorobenzamide is allowed to react with 5-trifluoromethylpyrazin-2-ylisocyanate to yield 1-(2-chlorobenzoyl)-3-(5-trifluoromethyl-2-pyrazinyl)urea, having a melting point of about 219°-220° C.

Herkunft & Nachweise