Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Piperazine | HCID 4837 | — |
| Edukt | 4-Fluorobenzenesulfonamide | HCID 120231 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | 4-(Piperazin-1-yl)benzene-1-sulfonamide | HCID 901897 | 96,1% |
Reaktionsschritte
A mixture of 4-fluorobenzenesulfonamide (6.95 g) and piperazine (17.1 g) in 30 mL of water is heated at 100° C. overnight. The solid is then collected, washed with water and toluene, and dried under reduced pressure to give 9.2 g of 4-(piperazin-1-yl)benzenesulfonamide; mp 219-221° C.; ms m/z 241; IR (mineral oil) 1160, 822, 1332, 608, 1593, 1137 cm-1. 1H NMR (DMSOd6) δ 2.81, 3.17, 2.3, 7.01, 7.07, 7.61.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US06013654 |
|---|
| Quelldatensatz | uspto-grants-2000_01 |
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| ORD ID | ord-04797938215e4ceb83bc79bdad90df9d |
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| Quellennotiz | uspto-grants-2000_01 |
|---|
