Methyl iodide → (E)-methyl 3-(3-methoxyphenyl)acrylate

HRID 84960Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 84960
[CH3:1][O:2][C:3]1[CH:4]=[C:5](/[CH:9]=[CH:10]/[C:11]([OH:13])=[O:12])[CH:6]=[CH:7][CH:8]=1.[C:14]([O-])([O-])=O.[K+].[K+].IC>CC(C)=O>[CH3:1][O:2][C:3]1[CH:4]=[C:5](/[CH:9]=[CH:10]/[C:11]([O:13][CH3:14])=[O:12])[CH:6]=[CH:7][CH:8]=1

Komponenten

5

Edukt 3

HCID 6328Methyl iodideHCID 11430Potassium CarbonateHCID 6376683-Methoxycinnamic Acid

Produkt 1

HCID 11041597(E)-methyl 3-(3-methoxyphenyl)acrylate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

A mixture of (E)-3-(3-methoxyphenyl)acrylic acid (3.56 g, 20 mmol). K2CO3 (3.1 g, 22 mmol), and iodomethane (4.0 g, 28 mmol) in acetone (20 mL) was heated to 70° C. for 16 hours. The mixture was concentrated and partitioned between water and ethyl acetate to afford the crude title compound.

Aufarbeitung

  1. concentrationThe mixture was concentrated
  2. custompartitioned between water and ethyl acetate

Quellen und Nachweise

ORD-Eintrag
ord-a6285a79c1b34b64965786eeecdd546f
Quelldatensatz
uspto-grants-2014_09
Patentnummer
US08846951B2

Notizen zur Reaktion

Wird geladen…