N'-t-butyl-N'-(3-methylbenzoyl)hydrazine → N'-t-butyl-N-(2-phenyl-3-methylpentanoyl)-N'-(3-toluoyl)hydrazine

HRID 849801

Reaktionsgleichung

Reaktionsgleichung von HRID 849801
[C:1]([N:5]([C:7]([C:9]1[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=1)=[O:8])[NH2:6])([CH3:4])([CH3:3])[CH3:2].[C:16]1([CH:22]([CH:26]([CH3:29])[CH2:27][CH3:28])[C:23](Cl)=[O:24])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>C1(C)C=CC=CC=1.[OH-].[Na+]>[C:1]([N:5]([C:7]([C:9]1[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=1)=[O:8])[NH:6][C:23](=[O:24])[CH:22]([C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1)[CH:26]([CH3:29])[CH2:27][CH3:28])([CH3:4])([CH3:3])[CH3:2]

Komponenten

5

Edukt 2

HCID 15452040N'-t-butyl-N'-(3-methylbenzoyl)hydrazineHCID 218860263-Methyl-2-phenylvaleryl chloride

Produkt 1

HCID 15452019N'-t-butyl-N-(2-phenyl-3-methylpentanoyl)-N'-(3-toluoyl)hydrazine

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 14798Sodium HydroxideKatalysatorHCID 1140TolueneLösungsmittel

Versuchsvorschrift

To a stirred suspension of N'-t-butyl-N'-(3-toluoyl)hydrazine (0.7 g) in toluene (10 ml) and aqueous sodium hydroxide (12 drops of 50% aqueous sodium hydroxide) was added dropwise 2-phenyl-3-methyl-pentanoyl chloride (1.0 g). The reaction mixture was stirred overnight, diluted with hexanes and the solids filtered. The solids were washed with hexane and air dried.

Aufarbeitung

  1. filtrationthe solids filtered
  2. washThe solids were washed with hexane and air
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-bcdc5b0e92e1419cba25cc680b139b5c
Quelldatensatz
uspto-grants-2000_01
Patentnummer
US06013836

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