Hydrochloric Acid → HCID 70293055, Verbindung
Reaktionsgleichung
[CH2:1]([O:3][C:4]([C:6]1[N:10]=[C:9]([CH:11]([N:23](C(OC(C)(C)C)=O)[CH3:24])[CH2:12][C:13]2[CH:22]=[CH:21][C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH:14]=2)[O:8][N:7]=1)=[O:5])[CH3:2].[ClH:32]>C(OCC)(=O)C>[ClH:32].[CH2:1]([O:3][C:4]([C:6]1[N:10]=[C:9]([CH:11]([NH:23][CH3:24])[CH2:12][C:13]2[CH:22]=[CH:21][C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH:14]=2)[O:8][N:7]=1)=[O:5])[CH3:2]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
5-(1-(N-Methyl-tert-butoxycarbonylamino)-2-(2-naphthyl)ethyl)-[1,2,4]oxadiazole-3-carboxylic acid ethyl ester (0.77 g, 1.8 mmol) was dissolved in a saturated solution of hydrogen chloride in ethyl acetate (15 ml). After 5 h at 20° C. the reaction mixture was concentrated in vacuo to give 0.72 g of (R) 5-(1-methylamino-2-(2-naphthyl)ethyl)-[1,2,4]oxadiazole-3-carboxylic acid ethyl ester hydrochloride.