t-Butyl bromide → Ethyl 1-(4-tert-butoxy-3-cyanophenyl)pyrazole-4-carboxylate
Reaktionsgleichung
[C:1]([C:3]1[CH:4]=[C:5]([N:10]2[CH:14]=[C:13]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH:12]=[N:11]2)[CH:6]=[CH:7][C:8]=1[OH:9])#[N:2].Br[C:21]([CH3:24])([CH3:23])[CH3:22]>>[C:21]([O:9][C:8]1[CH:7]=[CH:6][C:5]([N:10]2[CH:14]=[C:13]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH:12]=[N:11]2)=[CH:4][C:3]=1[C:1]#[N:2])([CH3:24])([CH3:23])[CH3:22]Komponenten
3
Versuchsvorschrift
The same reaction and treatment as in Example 5 using ethyl 1-(3cyano-4-hydroxyphenyl)pyrazole-4-carboxylate and 1-bromo-1,1-dimethylethane gives ethyl 1-(4-tert-butoxy-3-cyanophenyl)pyrazole-4-carboxylate.
Quellen und Nachweise
- ORD-Eintrag
- ord-3c4054984a5346f1a01ec90694c2ce79
- Quelldatensatz
- uspto-grants-2000_01
- Patentnummer
- US06015829