2-Methyl-4-phenylindene → (2-Methyl-4-phenylindenyl)(t-butylamino)dimethylsilane

HRID 850128Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 850128
[CH3:1][C:2]1[CH2:3][C:4]2[C:9]([CH:10]=1)=[C:8]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[CH:7]=[CH:6][CH:5]=2.[CH3:17][SiH:18]([N:20](Cl)[C:21]([CH3:24])([CH3:23])[CH3:22])[CH3:19]>C1COCC1>[CH3:1][C:2]1[CH:3]([Si:18]([NH:20][C:21]([CH3:24])([CH3:23])[CH3:22])([CH3:19])[CH3:17])[C:4]2[C:9]([CH:10]=1)=[C:8]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[CH:7]=[CH:6][CH:5]=2

Komponenten

4

Edukt 2

HCID 110745592-Methyl-4-phenylindeneHCID 123286153Dimethylsilyl(t-butylamino)chloride

Produkt 1

HCID 19366102(2-Methyl-4-phenylindenyl)(t-butylamino)dimethylsilaneAusbeute 82 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel3×

Versuchsvorschrift

2-methyl-4-phenylindene (synthesized substantially according to the technique reported in U.S. Pat. No. 5,329.033) (3.00 g, 0.014 moles) in THF (10 mL) was added dropwise to a stirring solution of KH (0.601 g, 0.0150 moles) in THF (50 mL). This mixture was allowed to stir for 16 hours. The solution was then filtered and added dropwise to a solution of dimethylsilyl(t-butylamino)chloride (2.41 g, 0.0145 moles) in THF (75 mL). This mixture was allowed to stir for 16 hours. After the reaction period the volatiles were removed and the residue extracted and filtered using hexane. Removal of the volatiles resulted in the isolation of the desired product as a light yellow oil (4.00 g, 82.0 percent).

Aufarbeitung

  1. filtrationThe solution was then filtered
  2. stirringto stir for 16 hours
  3. customAfter the reaction period the volatiles
  4. customwere removed
  5. extractionthe residue extracted
  6. filtrationfiltered
  7. customRemoval of the volatiles

Quellen und Nachweise

ORD-Eintrag
ord-3ab94c12469443d7acbbcb2807abbccd
Quelldatensatz
uspto-grants-2000_01
Patentnummer
US06015868

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