Quinoline → 5-Decenoic acid

HRID 851837

Reaktionsgleichung

Reaktionsgleichung von HRID 851837
Br[CH:2]([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:3][CH2:4][CH2:5][CH2:6][C:7]([O:9]C)=[O:8].N1C2C(=CC=CC=2)C=CC=1.C(OC)(=O)CCCC=CCCCC.C(OC)(=O)CCCCC=CCCC.C(O)(=O)CCCCC=CCCC>>[C:7]([OH:9])(=[O:8])[CH2:6][CH2:5][CH2:4][CH:3]=[CH:2][CH2:11][CH2:12][CH2:13][CH3:14]

Komponenten

6

Edukt 5

HCID 7047QuinolineHCID 22931398Methyl 6-bromodecanoateHCID 53401195Dec-6-enoic acidHCID 53854285HCID 53854285, VerbindungHCID 54534253Methyl 5-decenoate

Produkt 1

HCID 534008795-Decenoic acidAusbeute 35 %

Versuchsvorschrift

Methyl 6-bromodecanoate (1.2 g) and quinoline (1.2g) were mixed together, and then allowed to react at 240° C. for 5 minutes. After the reaction was completed, the reaction solution was extracted with ether, washed with dilute sulfuric acid, washed with water, dried, evaporated to remove the solvent, and then distilled, thereby giving a mixture of methyl 5-decenoate and methyl 6-decenoate (310 mg). The mixture was hydrolyzed in a coventional manner, thereby giving a mixture (270 mg) of 5-decenoic acid and 6-decenoic acid (1/1).

Aufarbeitung

  1. customto react at 240° C. for 5 minutes
  2. extractionthe reaction solution was extracted with ether
  3. washwashed with dilute sulfuric acid
  4. washwashed with water
  5. customdried
  6. customevaporated
  7. customto remove the solvent
  8. distillationdistilled
  9. customgiving

Quellen und Nachweise

ORD-Eintrag
ord-8dd77bdcdc434d79a2d242b7afbf50d2
Quelldatensatz
uspto-grants-2007_08
Patentnummer
US07252849B2

Verknüpfte Notizen

Wird geladen…