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HRID 851850Erstellt: 24. Oktober 2026

(6Rs,7rs)-5,5,6,7,8,8-hexamethyl-3,4,5,6,7,8-hexahydronaphthalen-2(1h)-one → Tonalide

https://huagongshe.com/de/reaction/851850

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt(6Rs,7rs)-5,5,6,7,8,8-hexamethyl-3,4,5,6,7,8-hexahydronaphthalen-2(1h)-oneHCID 69426524—
Edukt(6Rs,7rs)-3,5,5,6,7,8,8-heptamethyl-3,4,5,6,7,8-hexahydronaphthalen-1(2h)-oneHCID 69429922—
ProduktTonalideHCID 89440—

Reaktionsschritte

However, if there was added to the base the same amount of (6RS,7RS)-3,5,5,6,7,8,8-heptamethyl-3,4,5,6,7,8-hexahydronaphthalen-1(2H)-one or (6RS,7RS)-5,5,6,7,8,8-hexamethyl-3,4,5,6,7,8-hexahydronaphthalen-2(1H)-one the whole olfactif effect was closer to the one provided by Tonalide®. The effect obtained by the addition of (6RS,7RS) -5,5,6,7,8,8-hexamethyl-3,4,5,6,7,8-hexahydronaphthalen-2(1H)-one was also slightly more ambrette than the one imparted by (6RS,7RS)-3,5,5,6,7,8,8-heptamethyl-3,4,5,6,7,8-hexahydronaphthalen-1(2H)-one.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07253141B2
Quelldatensatzuspto-grants-2007_08
ORD IDord-5a81d00d0cd24f69b8d9110d25cda419
Quellennotizuspto-grants-2007_08