Catechol → Purpurogallin

HRID 8519

Reaktionsgleichung

Reaktionsgleichung von HRID 8519
[C:1]1([CH:9]=[CH:8][CH:7]=[C:5]([OH:6])[C:3]=1[OH:4])[OH:2].[C:10]1([C:12](=[CH:14][CH:15]=[CH:16]C=1)[OH:13])[OH:11].OO>CC(C)=O>[CH:9]1[C:8]2[CH:16]=[CH:15][CH:14]=[C:12]([OH:13])[C:10](=[O:11])[C:7]=2[C:5]([OH:6])=[C:3]([OH:4])[C:1]=1[OH:2]

Komponenten

5

Edukt 3

HCID 289CatecholHCID 784Hydrogen PeroxideHCID 1057Pyrogallol

Produkt 1

HCID 135403797PurpurogallinAusbeute 17,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

Pyrogallol (1 g) and catechol (1.5 g) were dissolved in a mixture of acetone-pH 5.0 phosphate citrate buffer (1:10, v/v, 50 mL), which contained 2 mg horseradish peroxidase. While being stirred, 2.0 mL of 3.13% H2O2 was added four times during 45 minutes. The reaction mixture was extracted by ethyl acetate (50 mL×3). After concentration, the residue was subjected to Sephadex LH 20 column eluted with acetone-water solvent system (45%). 300 mg Purpurogallin was obtained.

Aufarbeitung

  1. extractionThe reaction mixture was extracted by ethyl acetate (50 mL×3)
  2. concentrationAfter concentration
  3. washeluted with acetone-water solvent system (45%)

Quellen und Nachweise

ORD-Eintrag
ord-58d9642ade4b467aadb2af0aa39f7ca2
Quelldatensatz
uspto-grants-2006_08
Patentnummer
US07087790B2

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