HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dimethylformamide → (S)-1-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-phenoxy]-3-(methyl-phenethyl-amino)-propan-2-ol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dimethylformamide | HCID 6228 | — |
| Edukt | (S)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazole | HCID 11254641 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Lösungsmittel | N-Methylbenzeneethanamine | HCID 11503 | — |
| Produkt | (S)-1-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-phenoxy]-3-(methyl-phenethyl-amino)-propan-2-ol | HCID 9910031 | — |
Reaktionsschritte
The title compound is prepared from a mixture of (S)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazole in dimethylformamide and N-methylphenethylamine in ethanol essentially as described above in Example 21. Purity by LC/MS=100%, [M+H]+=421.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07253165B2 |
| Quelldatensatz | uspto-grants-2007_08 |
| ORD ID | ord-eb25839ff28c4e0c92654dc66d642db4 |
| Quellennotiz | uspto-grants-2007_08 |