1-Iodo-4-(trifluoromethoxy)benzene → 1-[3-(4-Trifluoromethoxy-phenyl)-prop-2-ynyl]-cyclobutanecarboxylic acid ethyl ester
Reaktionsgleichung
[CH2:1]([O:3][C:4]([C:6]1([CH2:10][C:11]#[CH:12])[CH2:9][CH2:8][CH2:7]1)=[O:5])[CH3:2].I[C:14]1[CH:19]=[CH:18][C:17]([O:20][C:21]([F:24])([F:23])[F:22])=[CH:16][CH:15]=1>>[CH2:1]([O:3][C:4]([C:6]1([CH2:10][C:11]#[C:12][C:14]2[CH:15]=[CH:16][C:17]([O:20][C:21]([F:22])([F:23])[F:24])=[CH:18][CH:19]=2)[CH2:9][CH2:8][CH2:7]1)=[O:5])[CH3:2]Komponenten
3
Versuchsvorschrift
In analogy to the procedure described in example 24E], reaction of 1-prop-2-ynyl-cyclobutanecarboxylic acid ethyl ester and 1-iodo-4-trifluoromethoxybenzene gave the title compound as yellow oil.
Quellen und Nachweise
- ORD-Eintrag
- ord-13c2fe204eae4d1b9807d569f14929b2
- Quelldatensatz
- uspto-grants-2007_08