Dimethylformamide dimethyl acetal → HCID 72466433, Verbindung
Reaktionsgleichung
[C:1]([C:3]1[CH:4]=[C:5]([NH:9][C:10]([NH2:12])=[S:11])[CH:6]=[CH:7][CH:8]=1)#[N:2].CO[CH:15](OC)[N:16]([CH3:18])[CH3:17]>>[CH3:15][N:16]([CH:18]=[N:12][C:10]([NH:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([C:1]#[N:2])[CH:4]=1)=[S:11])[CH3:17]Komponenten
3
Reaktionsbedingungen
- Temperatur
- 100 °C
Versuchsvorschrift
A mixture of 3 g (16.9 mmol) 1-(3-Cyanophenyl)-2-thiourea and 20 ml N,N-Dimethylformamide dimethyl acetal was heated to 100° C. for 1 h. After evaporation of the volatiles the precipitate was suspended in DCM, filtered and dried to yield 3.56 g (91%) of the title compound.
Aufarbeitung
- customAfter evaporation of the volatiles the precipitate
- filtrationfiltered
- customdried
Quellen und Nachweise
- ORD-Eintrag
- ord-8095ad6076e34d819f9678fc783a9013
- Quelldatensatz
- uspto-grants-2007_08
- Patentnummer
- US07253197B2
Notizen zur Reaktion
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