4-[2-[4-(Dibutylamino)phenyl]vinyl]benzyl alcohol → 4-{2-[4-(Dibutylamino)phenyl]ethenyl}benzaldehyde

HRID 85344Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 85344
[CH2:1]([N:5]([CH2:22][CH2:23][CH2:24][CH3:25])[C:6]1[CH:11]=[CH:10][C:9]([CH:12]=[CH:13][C:14]2[CH:21]=[CH:20][C:17]([CH2:18][OH:19])=[CH:16][CH:15]=2)=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH3:4]>ClCCl.[O-2].[O-2].[Mn+4]>[CH2:22]([N:5]([CH2:1][CH2:2][CH2:3][CH3:4])[C:6]1[CH:11]=[CH:10][C:9]([CH:12]=[CH:13][C:14]2[CH:21]=[CH:20][C:17]([CH:18]=[O:19])=[CH:16][CH:15]=2)=[CH:8][CH:7]=1)[CH2:23][CH2:24][CH3:25]

Komponenten

4

Edukt 1

HCID 680087414-[2-[4-(Dibutylamino)phenyl]vinyl]benzyl alcohol

Produkt 1

HCID 713628364-{2-[4-(Dibutylamino)phenyl]ethenyl}benzaldehydeAusbeute 64,1 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418406HCID 178418406, VerbindungKatalysatorHCID 6344DichloromethaneLösungsmittel2×

Versuchsvorschrift

In 30 ml of dichloromethane was suspended 6.0 g (69.0 mmol) of active manganese dioxide. Next, 1.17 g (3.45 mmol) of 4-[2-[4-(dibutylamino)phenyl]vinyl]benzyl alcohol was dissolved in dichloromethane and added to the suspension. After stirred at room temperature for 20 hours, the suspension was filtrated and the solvent was evaporated off. The residue was purified by silica gel column, chromatography to give 0.74 g of a yellow crystal (yield: 64.1%).

Aufarbeitung

  1. additionadded to the suspension
  2. filtrationthe suspension was filtrated
  3. customthe solvent was evaporated off
  4. customThe residue was purified by silica gel column, chromatography

Quellen und Nachweise

ORD-Eintrag
ord-7a2dbfd4835043ee919503c0d17b2a8b
Quelldatensatz
uspto-grants-2014_09
Patentnummer
US08846955B2

Notizen zur Reaktion

Wird geladen…